By Raffi V. Arkun
Special to the Mirror-Spectator
ARLINGTON, Mass. — Deep Origin is a company working on simulating molecular interactions to accelerate drug discovery, with a team of about 80 people, in locations spanning from California and Arlington, MA, to Europe and Armenia. Its specialty is making simulation tools, to predict, for example, how a novel medicine interacts with a disease-causing protein, or determine how proteins interact with each other, at either molecular or cellular scales. In the foreseeable future, the company plans to develop technology for simulating processes on organ, tissue, and organism levels. The long-term goal is to replace costly physical experiments in the lab with computer simulations, accelerating drug discovery and treatments. As the current Chief Scientific Operations Officer (CSOO), Dr. Ashot Papoyan oversees tech development and wet lab operations across 11 time zones. “The moonshot goal” of Deep Origin, Papoyan said, “is simulating life.”

Even as a child, Papoyan knew that biology was his calling, and today he loves his job so much that he said, “I don’t know what a 9 to 5 feels like.” Born in Yerevan to engineer parents, Papoyan was surrounded by the sciences throughout his whole youth. He graduated from Artashes Shahinyan Physics-Mathematics School (known colloquially as Phys-Math School), continuing his education at Yerevan State University. By 1999, Papoyan had completed a degree in biophysics and met his college sweetheart, Yelena Bisharyan, who was pursuing studies in genetics. During the summer prior to his senior year of university, Papoyan visited Cornell University in Ithaca, New York, to take summer classes. He also learned about the admission process, what differences exist between American and Armenian schools, the process of obtaining a doctorate, and much more.

Upon returning to Armenia after graduation, Papoyan’s life journey began with his marriage to Yelena. Soon after, he completed the standardized exams and gained admission to Cornell’s doctoral program in plant molecular biology. The couple relocated to Ithaca, NY, where Yelena also pursued her doctorate in immunology and cell and molecular biology.
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